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KMID : 1100620220090040345
Clinical and Experimental Emergency Medicine
2022 Volume.9 No. 4 p.345 ~ p.353
Development and validation of interpretable machine learning models for inpatient fall events and electronic medical record integration
Shim So-Yun

Yu Jae-Yong
Jekal Se-Yong
Song Yee-Jun
Moon Ki-Tae
Lee Ju-Hee
Yeom Kyung-Mi
Park Sook-Hyun
Cho In-Sook
Song Mi-Ra
Heo Se-Jin
Hong Jeong-Hee
Abstract
Objective: Falls are one of the most frequently occurring adverse events among hospitalized patients. The Morse Fall Scale, which has been widely used for fall risk assessment, has the two limitations of low specificity and difficulty in practical implementation. The aim of this study was to develop and validate an interpretable machine learning model for prediction of falls to be integrated in an electronic medical record (EMR) system.

Methods: This was a retrospective study involving a tertiary teaching hospital in Seoul, Korea. Based on the literature, 83 known predictors were grouped into seven categories. Interpretable fall event prediction models were developed using multiple machine learning models including gradient boosting and Shapley values.

Results: Overall, 191,778 cases with 272 fall events (0.1%) were included in the analysis. With the validation cohort of 2020, the area under the receiver operating curve (AUROC) of the gradient boosting model was 0.817 (95% confidence interval [CI], 0.720?0.904), better performance than random forest (AUROC, 0.801; 95% CI, 0.708?0.890), logistic regression (AUROC, 0.802; 95% CI, 0.721?0.878), artificial neural net (AUROC, 0.736; 95% CI, 0.650?0.821), and conventional Morse fall score (AUROC, 0.652; 95% CI, 0.570?0.715). The model¡¯s interpretability was enhanced at both the population and patient levels. The algorithm was later integrated into the current EMR system.

Conclusion: We developed an interpretable machine learning prediction model for inpatient fall events using EMR integration formats.
KEYWORD
Accidental falls, Machine learning, Patient safety, Nursing informatics
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